Previous IVF Failures2019-03-26T11:48:55-06:00

Previous IVF Failures

Many of CCRM’s patients have had failed IVF cycles at other fertility clinics. CCRM specializes in the management of the “poor responder” and those with previously unsuccessful cycles. We are recognized for our success rates and scientific achievements in the field of reproductive endocrinology and have helped thousands of couples achieve their dream of parenthood.


CCRM routinely incorporates innovative procedures in its treatment plans for the more “complicated” patient. Many of these innovations have been developed by and perfected by our clinical and laboratory teams resulting in publications in highly respected journals, including Fertility and Sterility, the Journal of Assisted Reproduction and Genetics, Reproductive Biomedicine Online, and Obstetrics and Gynecology. Some of these approaches which may be appropriate and will be discussed at a physician consultation include:

  • Personalized stimulation protocols based on an individual patient’s age, past history and evaluation of ovarian reserve test results. These include minimal stimulation techniques, the use of various priming methods, microdose flare protocols that were developed by our physicians, growth hormone, as well as pretreatment administration of specific antioxidant protocols to name just a few. Our innovative stimulation protocols and approach to managing the poor responder have been published in a host of journals, as well as book chapters.
  • Highly specialized sperm function testing to determine if additional innovative and individualized sperm separation techniques are appropriate. Intracytoplasmic sperm injection (ICSI) for patients with male factor infertility or those who previously had low fertilization rates or fertilization failure. Our program has published its high success with this technique and was one of the earlier programs in the United States to employ this technique.
  • In vitro maturation (IVM)
  • Co-culture
  • Blastocyst culture which was pioneered at CCRM with results published in the first randomized trial to address this technique.
  • Detailed evaluation of causes of previously unexplained implantation failure.
  • Comprehensive chromosomal screening (CCS) which not only will enhance the likelihood that an embryo will implant but may provide significant information to explain past unsuccessful cycles. The outcomes with this technique at CCRM have been published in several major journals.
  • Use of laboratory techniques and highly specialized culture medium that have been pioneered at CCRM.
  • Laser assisted hatching of embryos with outcomes from CCRM published in peer reviewed journals.
  • Some patients will require the use of oocyte donation (donor egg). This is a technique in which CCRM has excelled since the institution of our program.
  • Patients with uterine abnormalities which cannot be surgically corrected, medical conditions which make carrying a pregnancy extremely unsafe, or even those with recurrent unsuccessful transfer of genetically normal embryos with an otherwise normal appearing uterus may benefit from the use of a gestational carrier (surrogate).

Your CCRM doctor will review your medical records and may request additional testing before making final recommendations for your care.